Dominant Negative Effects of Human Follicle-Stimulating Hormone Receptor Expression-Deficient Mutants on Wild Type Receptor Cell Surface Expression. Rescue of Oligomerization-dependent Defective Receptor Expression by Using Cognate Decoys*

Current evidence indicates that G protein-coupled receptors form dimers that may affect biogenesis and membrane targeting of the complexed receptors. We here analyzed whether expression-deficient follicle-stimulating hormone receptor (FSHR) mutants exert dominant negative actions on wild-type FSHR c...

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Main Authors: Zariñán, Teresa, Perez-Solís, Marco A., Maya-Núñez, Guadalupe, Casas-González, Patricia, Conn, P. Michael, Dias, James A., Ulloa-Aguirre, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854281/
https://ncbi.nlm.nih.gov/pubmed/20206665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2010.02.027
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