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Ultra-Short Echo-Time MRI Detects Changes in Bone Mineralization and Water Content in OVX Rat Bone in Response to Alendronate Treatment

In this work we hypothesize that bisphosphonate treatment following ovariectomy manifests in increased phosphorus and decreased water concentration, both quantifiable nondestructively with ultra-short echo-time (UTE) (31)P and (1)H MRI techniques. We evaluated this hypothesis in ovariectomized (OVX)...

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Autori principali: Anumula, SeshaSailaja, Wehrli, Suzanne L., Magland, Jeremy, Wright, Alexander C., Wehrli, Felix W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854263/
https://ncbi.nlm.nih.gov/pubmed/20096815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2010.01.372
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