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Insulin secretion and insulin-producing tumors

Insulinomas are rare neuroendocrine tumors of pancreatic islet cells that retain the ability to produce and secrete insulin. In contrast to normally differentiated β-cells, insulinoma cells continue to secrete insulin and proinsulin at low blood glucose. This deregulated insulin secretion manifests...

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Bibliographic Details
Main Authors: Guettier, Jean-Marc, Gorden, Phillip
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853964/
https://ncbi.nlm.nih.gov/pubmed/20401170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/eem.09.83
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