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Beta Sheet 2 - Alpha Helix C Loop of Cytochrome P450 Reductase Serves as a Docking Site for Redox Partners
As a promiscuous redox partner, the biological role of cytochrome P450 reductase (CPR) depends significantly on protein-protein interactions. We tested a hypothesized CPR docking site by mutating D113, E115, and E116 to alanine and assaying activity toward various electron acceptors as a function of...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847005/ https://ncbi.nlm.nih.gov/pubmed/20152939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2010.02.003 |
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