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Beta Sheet 2 - Alpha Helix C Loop of Cytochrome P450 Reductase Serves as a Docking Site for Redox Partners

As a promiscuous redox partner, the biological role of cytochrome P450 reductase (CPR) depends significantly on protein-protein interactions. We tested a hypothesized CPR docking site by mutating D113, E115, and E116 to alanine and assaying activity toward various electron acceptors as a function of...

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Detalhes bibliográficos
Main Authors: Jang, Hyun-Hee, Jamakhandi, Arvind P., Sullivan, Shane Z., Yun, Chul-Ho, Hollenberg, Paul F., Miller, Grover P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847005/
https://ncbi.nlm.nih.gov/pubmed/20152939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2010.02.003
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