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Combined effects of the bisphosphonate, zoledronic acid and the aromatase inhibitor letrozole on breast cancer cells in vitro: evidence of synergistic interaction

BACKGROUND: Aromatase inhibitors are widely used in the treatment of oestrogen receptor-positive post-menopausal breast cancer. These patients may also be receiving the bisphosphonate, zoledronic acid (ZA) to prevent bone loss or reduce skeletal morbidity in the setting of advanced disease. The pote...

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Main Authors: Neville-Webbe, H L, Coleman, R E, Holen, I
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844031/
https://ncbi.nlm.nih.gov/pubmed/20160726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605579
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