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Appropriate maturation and folding of 16S rRNA during 30S subunit biogenesis are critical for translational fidelity

Ribosomal protein S5 is critical for small ribosomal subunit (SSU) assembly and is indispensable for SSU function. Previously, we identified a point mutation in S5, (G28D) that alters both SSU formation and translational fidelity in vivo, which is unprecedented for other characterized S5 mutations....

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Autors principals: Roy-Chaudhuri, Biswajoy, Kirthi, Narayanaswamy, Culver, Gloria M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842029/
https://ncbi.nlm.nih.gov/pubmed/20176963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912305107
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