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Diminishing Efficacy of Combination Therapy, Response-Heterogeneity, and Treatment Intolerance Limit the Attainability of Tight Risk Factor Control in Patients with Diabetes
OBJECTIVE: To evaluate the attainability of tight risk factor control targets for three diabetes risk factors and to assess the degree of polypharmacy required. DATA SOURCES/STUDY SETTING: National Health and Nutrition Examination Survey-III. STUDY DESIGN: We simulated a strategy of “treating to tar...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838154/ https://ncbi.nlm.nih.gov/pubmed/20070387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1475-6773.2009.01075.x |
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