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Novel lines of Pax6(-/- )embryonic stem cells exhibit reduced neurogenic capacity without loss of viability

BACKGROUND: Embryonic stem (ES) cells can differentiate into all cell types and have been used extensively to study factors affecting neuronal differentiation. ES cells containing mutations in known genes have the potential to provide useful in vitro models for the study of gene function during neur...

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Detalhes bibliográficos
Main Authors: Quinn, Jane C, Molinek, Michael, Nowakowski, Tomasz J, Mason, John O, Price, David J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837049/
https://ncbi.nlm.nih.gov/pubmed/20178645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-26
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