Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks

Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide and is considered to be the outcome of chronic liver inflammation. Currently, the main treatment for HCC is surgical resection. However, survival rates are suboptimal partially because of tumor recurrence in the...

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Autori principali: Barash, Hila, R. Gross, Eitan, Edrei, Yifat, Ella, Ezra, Israel, Ariel, Cohen, Irit, Corchia, Nathalie, Ben-Moshe, Tehila, Pappo, Orit, Pikarsky, Eli, Goldenberg, Daniel, Shiloh, Yosef, Galun, Eithan, Abramovitch, Rinat
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836653/
https://ncbi.nlm.nih.gov/pubmed/20133864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908867107
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