Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks

Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide and is considered to be the outcome of chronic liver inflammation. Currently, the main treatment for HCC is surgical resection. However, survival rates are suboptimal partially because of tumor recurrence in the...

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Detalles Bibliográficos
Main Authors: Barash, Hila, R. Gross, Eitan, Edrei, Yifat, Ella, Ezra, Israel, Ariel, Cohen, Irit, Corchia, Nathalie, Ben-Moshe, Tehila, Pappo, Orit, Pikarsky, Eli, Goldenberg, Daniel, Shiloh, Yosef, Galun, Eithan, Abramovitch, Rinat
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836653/
https://ncbi.nlm.nih.gov/pubmed/20133864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908867107
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