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Roles of B cells in rheumatoid arthritis

B lymphocytes play several critical roles in the pathogenesis of rheumatoid arthritis. They are the source of the rheumatoid factors and anticitrullinated protein antibodies, which contribute to immune complex formation and complement activation in the joints. B cells are also very efficient antigen...

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Bibliographic Details
Main Authors: Silverman, Gregg J, Carson, Dennis A
Format: Artigo
Language:Inglês
Published: BioMed Central 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2833442/
https://ncbi.nlm.nih.gov/pubmed/15180890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1010
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