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Modulation of KvAP Unitary Conductance and Gating by 1-Alkanols and Other Surface Active Agents

The actions of alcohols and anesthetics on ion channels are poorly understood. Controversy continues about whether bilayer restructuring is relevant to the modulatory effects of these surface active agents (SAAs). Some voltage-gated K channels (Kv), but not KvAP, have putative low affinity alcohol-b...

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Détails bibliographiques
Auteurs principaux: Finol-Urdaneta, Rocio K., McArthur, Jeffrey R., Juranka, Peter F., French, Robert J., Morris, Catherine E.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830433/
https://ncbi.nlm.nih.gov/pubmed/20197029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.10.053
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