The Cannabinoid 1 Receptor (CNR1) 1359 G/A Polymorphism Modulates Susceptibility to Ulcerative Colitis and the Phenotype in Crohn's Disease

BACKGROUND: Recent evidence suggests a crucial role of the endocannabinoid system, including the cannabinoid 1 receptor (CNR1), in intestinal inflammation. We therefore investigated the influence of the CNR1 1359 G/A (p.Thr453Thr; rs1049353) single nucleotide polymorphism (SNP) on disease susceptibi...

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Hauptverfasser: Storr, Martin, Emmerdinger, Dominik, Diegelmann, Julia, Pfennig, Simone, Ochsenkühn, Thomas, Göke, Burkhard, Lohse, Peter, Brand, Stephan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829088/
https://ncbi.nlm.nih.gov/pubmed/20195480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009453
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