The accumulation and metabolism of zidovudine in 3T3-F442A pre-adipocytes

BACKGROUND AND PURPOSE: Cultured pre-adipocytes accumulate and metabolize zidovudine (ZDV), but its mode of accumulation into these cells is unclear. We investigated the mode of accumulation of [(3)H]-ZDV, and the impact of changes in external pH and modulators of drug transporters on its accumulati...

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Bibliographic Details
Main Authors: Janneh, Omar, Owen, Andrew, Bray, Patrick G, Back, David J, Pirmohamed, Munir
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2010
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825369/
https://ncbi.nlm.nih.gov/pubmed/20015290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00552.x
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