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siah-1 Protein Is Necessary for High Glucose-induced Glyceraldehyde-3-phosphate Dehydrogenase Nuclear Accumulation and Cell Death in Müller Cells

The translocation and accumulation of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in the nucleus has closely been associated with cell death induction. However, the mechanism of this process has not been completely understood. The E3 ubiquitin ligase siah-1 (seven in absentia homolog 1) has rec...

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Bibliografiset tiedot
Päätekijät: Yego, E. Chepchumba K., Mohr, Susanne
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823464/
https://ncbi.nlm.nih.gov/pubmed/19940145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.083907
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