Hypercholesterolemia induces side-specific phenotype changes and PPAR&[gamma] pathway activation in swine aortic valve endothelium

BACKGROUND: The endothelium of normal aortic valves expresses different phenotypes on the aortic and ventricular sides. On the aortic side, which is susceptible to aortic valve sclerosis (AVS), there is a balanced co-expression of both pro-pathological and protective pathways. Side-specific global g...

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Bibliographic Details
Main Authors: Guerraty, Marie A., Grant, Gregory R., Karanian, John W., Chiesa, Oscar A., Pritchard, William F., Davies, Peter F.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823293/
https://ncbi.nlm.nih.gov/pubmed/19926833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.198549
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