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TCDD and a Putative Endogenous AhR Ligand, ITE, Elicit the Same Immediate Changes in Gene Expression in Mouse Lung Fibroblasts

The aryl hydrocarbon receptor (AhR), a ligand-dependent transcription factor, mediates toxicity of several classes of xenobiotics and also has important physiological roles in differentiation, reproduction, and immunity, although the endogenous ligand(s) mediating these functions is/are as yet unide...

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Detalhes bibliográficos
Main Authors: Henry, Ellen C., Welle, Stephen L., Gasiewicz, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819971/
https://ncbi.nlm.nih.gov/pubmed/19933214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp285
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