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Transient muscle paralysis disrupts bone homeostasis by rapid degradation of bone morphology

We have previously shown that transient paralysis of murine hindlimb muscles causes profound degradation of both trabecular and cortical bone in the adjacent skeleton within 3 weeks. Morphologically, the acute loss of bone tissue appeared to arise primarily due to osteoclastic bone resorption. Given...

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Autors principals: Poliachik, Sandra L., Bain, Steven D., Threet, DeWayne, Huber, Philippe, Gross, Ted S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818332/
https://ncbi.nlm.nih.gov/pubmed/19857614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2009.10.025
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