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Sharp-1 modulates the cellular response to DNA damage
DNA damage checkpoints are essential for maintenance of genome integrity. We report here that inducible overexpression of the transcription factor Sharp-1 results in an S and G2/M cell cycle arrest, concomitant with the upregulation of Brca1 and GADD45α expression. In addition, we show that endogeno...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812643/ https://ncbi.nlm.nih.gov/pubmed/20006609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.12.011 |
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