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Resistance to Bacillus anthracis Infection Mediated by a Lethal Toxin Sensitive Allele of Nalp1b/Nlrp1b

Pathogenesis of Bacillus anthracis is associated with the production of lethal toxin (LT), which activates the murine Nalp1b/Nlrp1b inflammasome and induces caspase-1-dependent pyroptotic death in macrophages and dendritic cells. Here, we investigated the effect of allelic variation of Nlrp1b on the...

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Bibliografski detalji
Glavni autori: Terra, Jill K., Cote, Christopher K., France, Bryan, Jenkins, Amy L., Bozue, Joel A., Welkos, Susan L., LeVine, Steven M., Bradley, Kenneth A.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811128/
https://ncbi.nlm.nih.gov/pubmed/19949100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903114
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