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Extracellular Matrix Remodeling, Integrin Expression, and Downstream Signaling Pathways Influence the Osteogenic Differentiation of Mesenchymal Stem Cells on Poly(Lactide-Co-Glycolide) Substrates

The possibility of using multipotent adult bone marrow–derived mesenchymal stem cells (MSCs) for tissue-engineering applications hinges on the ability to predictably control their differentiation. Previously, we showed the osteogenic potential of adult bone marrow–derived MSCs cultured on thin films...

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Autori principali: Kundu, Anup K., Khatiwala, Chirag B., Putnam, Andrew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810215/
https://ncbi.nlm.nih.gov/pubmed/18767971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2008.0055
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