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U-shaped dose-dependent effects of BmK AS, a unique scorpion polypeptide toxin, on voltage-gated sodium channels
BACKGROUND AND PURPOSE: Buthus martensi Karsch (BmK) AS is a scorpion polypeptide toxin, said to target the voltage-gated sodium channels (VGSCs). However, the mechanism of action of BmK AS on the VGSCs has yet to be defined. EXPERIMENTAL APPROACH: We examined the electrophysiological effects of BmK...
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Auteurs principaux: | , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Blackwell Publishing Ltd
2009
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2807651/ https://ncbi.nlm.nih.gov/pubmed/19912232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00471.x |
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