U-shaped dose-dependent effects of BmK AS, a unique scorpion polypeptide toxin, on voltage-gated sodium channels

BACKGROUND AND PURPOSE: Buthus martensi Karsch (BmK) AS is a scorpion polypeptide toxin, said to target the voltage-gated sodium channels (VGSCs). However, the mechanism of action of BmK AS on the VGSCs has yet to be defined. EXPERIMENTAL APPROACH: We examined the electrophysiological effects of BmK...

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Hlavní autoři: Zhu, Mang-Mang, Tao, Jie, Tan, Miao, Yang, Hong-tian, Ji, Yong-Hua
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2009
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807651/
https://ncbi.nlm.nih.gov/pubmed/19912232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00471.x
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