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Molecular footprints of a germinal center derivation of human IgM(+)(IgD(+))CD27(+) B cells and the dynamics of memory B cell generation
The origin of IgM(+)CD27(+) B lymphocytes with mutated IgV genes, which account for ∼20% of human peripheral blood (PB) B cells, is controversially discussed. A generation in a primary diversification pathway, in T cell–independent immune responses, or in T cell–dependent germinal center (GC) reacti...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806629/ https://ncbi.nlm.nih.gov/pubmed/19917772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091087 |
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