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Binding of Natural and Synthetic Polyphenols to Human Dihydrofolate Reductase
Dihydrofolate reductase (DHFR) is the subject of intensive investigation since it appears to be the primary target enzyme for antifolate drugs. Fluorescence quenching experiments show that the ester bond-containing tea polyphenols (-)-epigallocatechin gallate (EGCG) and (-)-epicatechin gallate (ECG)...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Molecular Diversity Preservation International (MDPI)
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802001/ https://ncbi.nlm.nih.gov/pubmed/20054477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms10125398 |
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