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Caenorhabditis elegans P(5B)-type ATPase CATP-5 operates in polyamine transport and is crucial for norspermidine-mediated suppression of RNA interference

Physiological polyamines are required in various biological processes. In the current study, we used norspermidine, a structural analog of the natural polyamine spermidine, to investigate polyamine uptake in the model organism Caenorhabditis elegans. Norspermidine was found to have two remarkable ef...

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Hlavní autoři: Heinick, Alexander, Urban, Katja, Roth, Stefan, Spies, Danica, Nunes, Frank, Phanstiel, Otto, Liebau, Eva, Lüersen, Kai
Médium: Artigo
Jazyk:Inglês
Vydáno: The Federation of American Societies for Experimental Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797033/
https://ncbi.nlm.nih.gov/pubmed/19762559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-135889
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