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Neuronal IP(3) 3-Kinase is an F-actin–bundling Protein: Role in Dendritic Targeting and Regulation of Spine Morphology

The actin microstructure in dendritic spines is involved in synaptic plasticity. Inositol trisphosphate 3-kinase A (ITPKA) terminates Ins(1,4,5)P(3) signals emanating from spines and also binds filamentous actin (F-actin) through its amino terminal region (amino acids 1-66, N66). Here we investigate...

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Autores principales: Johnson, Hong W., Schell, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793293/
https://ncbi.nlm.nih.gov/pubmed/19846664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-01-0083
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