Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine(245)

Killer immunoglobulin-like receptors (KIRs) play an essential role in the regulation of natural killer cell functions. KIR genes are highly polymorphic in nature, showing both haplotypic and allelic variations among people. We demonstrated in both in vitro and in vivo models a significant heterogene...

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Main Authors: Bari, Rafijul, Bell, Teresa, Leung, Wai-Hang, Vong, Queenie P., Chan, Wing Keung, Das Gupta, Neha, Holladay, Martha, Rooney, Barbara, Leung, Wing
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2009
主題:
Immunobiology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792213/
https://ncbi.nlm.nih.gov/pubmed/19828694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-231977
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