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Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine(245)
Killer immunoglobulin-like receptors (KIRs) play an essential role in the regulation of natural killer cell functions. KIR genes are highly polymorphic in nature, showing both haplotypic and allelic variations among people. We demonstrated in both in vitro and in vivo models a significant heterogene...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2792213/ https://ncbi.nlm.nih.gov/pubmed/19828694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-231977 |
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