Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine(245)

Killer immunoglobulin-like receptors (KIRs) play an essential role in the regulation of natural killer cell functions. KIR genes are highly polymorphic in nature, showing both haplotypic and allelic variations among people. We demonstrated in both in vitro and in vivo models a significant heterogene...

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Autores principales: Bari, Rafijul, Bell, Teresa, Leung, Wai-Hang, Vong, Queenie P., Chan, Wing Keung, Das Gupta, Neha, Holladay, Martha, Rooney, Barbara, Leung, Wing
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2009
Materias:
Immunobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792213/
https://ncbi.nlm.nih.gov/pubmed/19828694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-231977
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