Regulation of CD45 Alternative Splicing by Heterogeneous Ribonucleoprotein, hnRNPLL

The transition from naïve to activated T cells is marked by alternative splicing of pre-mRNA encoding the transmembrane phosphatase CD45. Using a short hairpin RNA interference screen, we identified heterogeneous ribonucleoprotein L-like (hnRNPLL) as a critical inducible regulator of CD45 alternativ...

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Hlavní autoři: Oberdoerffer, Shalini, Moita, Luis Ferreira, Neems, Daniel, Freitas, Rui P., Hacohen, Nir, Rao, Anjana
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791692/
https://ncbi.nlm.nih.gov/pubmed/18669861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1157610
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