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Activation of FcγR1 on monocytes triggers differentiation into immature dendritic cells that induce autoreactive T cell responses

The formation of immune complexes results in activation of the innate immune system and subsequent induction of host inflammatory responses. In particular, the binding of IgG immune complexes to Fcγ receptors (FcγR) on monocytes triggers potent inflammatory responses leading to tissue injury in dise...

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Hlavní autoři: Tanaka, Motoyuki, Krutzik, Stephan R., Sieling, Peter A., Lee, Delphine, Rea, Thomas H., Modlin, Robert L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790276/
https://ncbi.nlm.nih.gov/pubmed/19635920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801683
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