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Aldose Reductase: A Novel Therapeutic Target for Inflammatory Pathologies

Aldose reductase (AR), that catalyzes the rate limiting step of the polyol pathway of glucose metabolism, besides reducing glucose to sorbitol, reduces a number of lipid peroxidation –derived aldehydes and their glutathione conjugates. Recent studies suggest that apart from its involvement in diabet...

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Autori principali: Ramana, Kota V, Srivastava, Satish K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787653/
https://ncbi.nlm.nih.gov/pubmed/19778627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2009.09.009
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