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Aldose Reductase: A Novel Therapeutic Target for Inflammatory Pathologies
Aldose reductase (AR), that catalyzes the rate limiting step of the polyol pathway of glucose metabolism, besides reducing glucose to sorbitol, reduces a number of lipid peroxidation –derived aldehydes and their glutathione conjugates. Recent studies suggest that apart from its involvement in diabet...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787653/ https://ncbi.nlm.nih.gov/pubmed/19778627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2009.09.009 |
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