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Suboptimal Activation of Protease-activated Receptors Enhances α(2)β(1) Integrin-mediated Platelet Adhesion to Collagen
Thrombin and fibrillar collagen are potent activators of platelets at sites of vascular injury. Both agonists cause platelet shape change, granule secretion, and aggregation to form the primary hemostatic plug. Human platelets express two thrombin receptors, protease-activated receptors 1 and 4 (PAR...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787326/ https://ncbi.nlm.nih.gov/pubmed/19815553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.020990 |
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