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Improved entrapment efficiency of hydrophilic drug substance during nanoprecipitation of poly(I)lactide nanoparticles

The purpose of this research was to improve the entrapment efficiency of a model hydrophilic drug substance, sodium cromoglycate, loaded inside polylactic acid nanoparticles by a modified nanoprecipitation method. The effect of formulation parameters was studied to improve the entrapment efficiency...

詳細記述

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書誌詳細
主要な著者: Peltonen, Leena, Aitta, Johanna, Hyvönen, Samuli, Karjalainen, Milja, Hirvonen, Jouni
フォーマット: Artigo
言語:Inglês
出版事項: Springer-Verlag 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784850/
https://ncbi.nlm.nih.gov/pubmed/15198537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt050116
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