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Improved entrapment efficiency of hydrophilic drug substance during nanoprecipitation of poly(I)lactide nanoparticles
The purpose of this research was to improve the entrapment efficiency of a model hydrophilic drug substance, sodium cromoglycate, loaded inside polylactic acid nanoparticles by a modified nanoprecipitation method. The effect of formulation parameters was studied to improve the entrapment efficiency...
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Auteurs principaux: | , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
Springer-Verlag
2009
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784850/ https://ncbi.nlm.nih.gov/pubmed/15198537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt050116 |
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