Antigen-Induced Increases in Pulmonary Mast Cell Progenitor Numbers Depend on IL-9 and CD1d-Restricted NKT Cells

Pulmonary mast cell progenitor (MCp) numbers increase dramatically in sensitized and aerosolized Ag-challenged mice. This increase depends on CD4(+) T cells, as no MCp increase occurs in the lungs of sensitized wild-type (WT) mice after mAb depletion of CD4(+) but not CD8(+) cells before aerosol Ag...

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Bibliographic Details
Main Authors: Jones, Tatiana G., Hallgren, Jenny, Humbles, Alison, Burwell, Timothy, Finkelman, Fred D., Alcaide, Pilar, Austen, K. Frank, Gurish, Michael F.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782612/
https://ncbi.nlm.nih.gov/pubmed/19783672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901471
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