The bioavailability and airway clearance of the steroid component of budesonide/formoterol and salmeterol/fluticasone after inhaled administration in patients with COPD and healthy subjects: a randomized controlled trial

BACKGROUND: Airway absorption and bioavailability of inhaled corticosteroids (ICSs) may be influenced by differences in pharmacokinetic properties such as lipophilicity and patient characteristics such as lung function. This study aimed to further investigate and clarify the distribution of budesoni...

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Autori principali: Dalby, Chris, Polanowski, Tomasz, Larsson, Thomas, Borgström, Lars, Edsbäcker, Staffan, Harrison, Tim W
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780403/
https://ncbi.nlm.nih.gov/pubmed/19878590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-10-104
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