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NKG2D Ligand Expression in Human Colorectal Cancer Reveals Associations with Prognosis and Evidence for Immunoediting

PURPOSE: NKG2D binds to cellular ligands of the MIC and ULBP/RAET family. These ligands have restricted expression in normal tissue, but are frequently expressed on primary tumors. The role of NKG2D ligands is thought to be important in carcinogenesis but prognostic impact has not been investigated...

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Autors principals: McGilvray, Roger W, Eagle, Robert A, Watson, Nicholas FS, Al-Attar, Ahmad, Ball, Graham, Jafferji, Insiya, Trowsdale, John, Durrant, Lindy G
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778653/
https://ncbi.nlm.nih.gov/pubmed/19861434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0991
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