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The First Transmembrane Domain of the Hepatitis B Virus Large Envelope Protein Is Crucial for Infectivity

The early steps of the hepatitis B virus (HBV) life cycle are still poorly understood. Indeed, neither the virus receptor at the cell surface nor the mechanism by which nucleocapsids are delivered to the cytosol of infected cells has been identified. Extensive mutagenesis studies in pre-S1, pre-S2,...

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Autores principales: Lepère-Douard, Charlotte, Trotard, Maud, Le Seyec, Jacques, Gripon, Philippe
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772721/
https://ncbi.nlm.nih.gov/pubmed/19740987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01026-09
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