Expression Patterns of Cardiac Myofilament Proteins – Genomic and Protein Analysis of Surgical Myectomy Tissue from Patients with Obstructive Hypertrophic Cardiomyopathy

BACKGROUND: Mutations in myofilament proteins, most commonly MYBPC3-encoded myosin binding protein C and MYH7-encoded β-myosin heavy chain, can cause hypertrophic cardiomyopathy (HCM). Despite significant advances in structure-function relationships pertaining to the cardiac sarcomere, there is limi...

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Main Authors: Theis, Jeanne L., Bos, J. Martijn, Theis, Jason D., Miller, Dylan V., Dearani, Joseph A., Schaff, Hartzell V., Gersh, Bernard J., Ommen, Steve R., Moss, Richard L., Ackerman, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765062/
https://ncbi.nlm.nih.gov/pubmed/19808356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.108.789735
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