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Epigenetic silencing contributes to the loss of BRMS1 expression in breast cancer

Breast Cancer Metastasis Suppressor 1 (BRMS1) suppresses metastasis of human breast cancer, ovarian cancer and melanoma in athymic mice. Studies have also shown that BRMS1 is significantly downregulated in some breast tumors, especially in metastatic disease. However, the mechanisms which regulate B...

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Huvudupphovsmän: Metge, Brandon J., Frost, Andra R., King, Judy A., Dyess, Donna Lynn, Welch, Danny R., Samant, Rajeev S., Shevde, Lalita A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763604/
https://ncbi.nlm.nih.gov/pubmed/18566899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-008-9187-x
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