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Peak Thrombin Generation and Subsequent Venous Thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)

BACKGROUND: Thrombin is an enzyme essential to the acceleration of the coagulation cascade and the conversion of fibrinogen to clottable fibrin. OBJECTIVES: We evaluated the relation of basal peak thrombin generation to risk of future VTE, and determined whether associations were independent of othe...

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Bibliographische Detailangaben
Hauptverfasser: Lutsey, Pamela L., Folsom, Aaron R., Heckbert, Susan R., Cushman, Mary
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763356/
https://ncbi.nlm.nih.gov/pubmed/19656279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2009.03561.x
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