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Early Activation of FGF and Nodal Pathways Mediates Cardiac Specification Independently of Wnt/β-Catenin Signaling

BACKGROUND: Cardiac induction, the first step in heart development in vertebrate embryos, is thought to be initiated by anterior endoderm during gastrulation, but what the signals are and how they act is unknown. Several signaling pathways, including FGF, Nodal, BMP and Wnt have been implicated in c...

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Bibliografiska uppgifter
Huvudupphovsmän: Samuel, Lee J., Latinkić, Branko V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763344/
https://ncbi.nlm.nih.gov/pubmed/19862329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007650
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