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A dual reporter approach to quantify defects in mRNA processing
Splicing and nuclear export are vital components of eukaryotic gene expression. Defects in splicing due to cis-mutations are known to cause a number of human diseases. Here we present a dual reporter system that can be utilized to look at splicing or export deficiencies resulting from an insufficien...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760683/ https://ncbi.nlm.nih.gov/pubmed/19733147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2009.08.040 |
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