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Monitoring Peptidase Activities in Complex Proteomes by MALDI-TOF Mass Spectrometry

Measuring enzymatic activities in biological fluids is a form of activity-based proteomics and may be utilized as a means of developing disease biomarkers. Activity-based assays allow amplification of output signals, thus potentially visualizing low-abundant enzymes on a virtually transparent whole-...

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Main Authors: Villanueva, Josep, Nazarian, Arpi, Lawlor, Kevin, Tempst, Paul
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760592/
https://ncbi.nlm.nih.gov/pubmed/19617888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2009.88
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