FAK Deficiency in Cells Contributing to the Basal Lamina Results in Cortical Abnormalities Resembling Congenital Muscular Dystrophies

Targeted deletion of focal adhesion kinase (fak) in the developing dorsal forebrain resulted in local disruptions of the cortical basement membrane located between the neuroepithelium and pia-meninges. At disruption sites, clusters of neurons invaded the marginal zone. Retraction of radial glial end...

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Main Authors: Beggs, Hilary E., Schahin-Reed, Dorreyah, Zang, Keling, Goebbels, Sandra, Nave, Klaus-Armin, Gorski, Jessica, Jones, Kevin R., Sretavan, David, Reichardt, Louis F.
Format: Artigo
Language:Inglês
Published: 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758566/
https://ncbi.nlm.nih.gov/pubmed/14642275
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