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Flexible Filaments for in vivo Imaging and Delivery: Persistent Circulation of Filomicelles Opens the Dosage Window for Sustained Tumor Shrinkage

Shape effects of synthetic carriers are largely unexplored in vivo, although recent findings suggest that flexible filaments can persist in the circulation even if microns in length. Here, to better assess biodistribution, a near infrared fluorophore (NIRF) was incorporated into such block copolymer...

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Detalles Bibliográficos
Main Authors: Christian, David A., Cai, Shenshen, Garbuzenko, Olga B., Harada, Takamasa, Zajac, Allison L., Minko, Tamara, Discher, Dennis E.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757530/
https://ncbi.nlm.nih.gov/pubmed/19249859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900022m
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